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NIH TRAINING GRANT ABSTRACT

POSTDOCTORAL TRAINING IN TRAUMA AND BURNS

Abstract

   Thermal injury remains a major medical problem in the United States and throughout most of the world.  The nature of burn pathophysiology however is not well defined.  Basic researchers are active in this field, but trained clinicians are needed to make the knowledge generated useful in patient care.  The principal objective of this proposal is to train physicians and scientists to perform research and interpret data; to apply resulting new methodology in a clinical environment; to communicate findings to the medical community.

   The program is divided into four major research areas: cardiopulmonary physiology; endocrinology and metabolism; wound healing; and molecular biology.  Trainee’s work and study with a multidisciplinary group of faculty members, most of who have been working together for over 12 years.  The major features of the program are didactic training and hands-on research.  Didactic training includes a basic core curriculum in which all trainees participate in research projects of other trainees and investigators, and cooperation in research is emphasized.  All projects proceed under the close tutelage of a mentor, and with collaboration of other program faculty members.

   This proposal calls for 3 trainees for each year proposed at a post-graduate, year-five level.  This level could fluctuate based upon the qualifications of the candidates.  Candidates require either an M.D. or a Ph.D. and at least two years of postdoctoral training.

   Research and training take place at the Shriners Burns Hospital (SBH) and the University of Texas Medical Branch (UTMB).  SBH is located on the UTMB campus in Galveston, Texas.

   SBH facilities include 40 laboratories specifically designed for research in wound healing, tissue culture, metabolism, microbiology, electron microscopy, small animal experiments, analytical chemistry, and stable and radioactive isotope analysis.  Clinical labs are available at both SBH and UTMB.

   Other UTMB facilities pertinent to the program include the Protein Chemistry Lab, the Ovine Intensive Care Unit and the Clinical Research Center.

    NIH Training Grant – 5 T32 GM 08256